DMEM Low Glucose Pyruvate (500 mL) Reagent – A Balanced Medium for Sensitive Cell Culture Workflows

DMEM Low Glucose Pyruvate (500 mL) Reagent is specifically designed to support delicate and primary cell lines that require a controlled and stable nutrient environment. With an optimized formulation that balances energy sources and metabolic support, this medium is a preferred choice among researchers working in diverse cellular and molecular applications.
In the rapidly evolving world of molecular biology, choosing the right Cell Culture Reagents is crucial for ensuring healthy cell growth and consistent experimental results.

What is DMEM Low Glucose Pyruvate (500 mL) Reagent?

DMEM (Dulbecco’s Modified Eagle Medium) is a widely used culturing medium across global research laboratories. This Low Glucose version, enriched with pyruvate, offers a gentler and more physiologically relevant energy level for cells that grow best under mild metabolic conditions.

Pyruvate acts as an additional energy substrate that supports cell survival, viability, and metabolic balance—particularly important for primary cells, neurons, stem cells, and slow-dividing cell types. This makes the reagent an indispensable Lab Reagent for sensitive and precision-driven experiments.

Specifications of DMEM Low Glucose Pyruvate (500 mL) 

Cell Line: HeLa, 293, Cos-7, and PC-12
Cell Type: Primary Fibroblasts, Neurons, Glial Cells, HUVECs, Smooth Muscle Cells
Classification: Animal Origin-free
Concentration: 1 X
Form: Liquid
Product Type: DMEM (Dulbecco’s Modified Eagle Medium)
Serum Level: Standard Serum Supplementation
Sterility: Sterile-filtered
Sterilization Method: Sterile-filtered
With Additives: Low Glucose, GlutaMAX, Phenol Red, Sodium Pyruvate
Without Additives: No Sodium Pyruvate
Application: Mammalian cell culture
Manufacturing Quality: cGMP-compliant under the ISO 13485 standard
Product Line: GlutaMAX™
Quantity: 500 mL
Shipping Condition: Room Temperature
Content And Storage: Storage conditions: 2-8° C. Protect from light
Shipping conditions: Ambient
Shelf life: 12 months from date of manufacture

Key Features of DMEM Low Glucose Pyruvate (500 mL) Reagent

• Low Glucose Formulation: Provides a controlled nutrient environment ideal for primary and metabolically sensitive cell lines.
• Pyruvate-Enriched Medium: Supports cellular metabolism, boosts viability, and enhances energy efficiency.
• High-Quality Lab Chemicals: Manufactured using premium-grade ingredients to ensure purity and reproducibility.
• Suitable for Molecular Biology Applications: Ideal for gene expression studies, protein analysis, drug screening, and more.
• Compatible with Blot Reagents: Ensures reliable performance in Western blotting and other blot-based assays.
• Packaged in a Convenient 500 mL Bottle: Easy to use, sterile, and ready for routine laboratory workflows. 

Benefits 

• Promotes Healthy Cell Growth: Balanced nutrients help support sensitive cell types without overstimulation.
• Reduces Metabolic Stress: Low glucose minimizes oxidative stress and promotes physiological cell behavior.
• Enhanced Stability & Viability: Pyruvate addition strengthens metabolic pathways for long-term culture.
• Superior Reproducibility: High-quality formulation ensures consistent performance in all experiments.
• Versatile Research Use
• Suitable for cancer studies, primary cell culture, metabolic assays, and molecular biology workflows.

Conclusion

DMEM Low Glucose Pyruvate (500 mL) Reagent is an expertly formulated medium designed to deliver stability, reliability, and metabolic balance in cell culture. With its low glucose concentration and pyruvate supplementation, it provides a nurturing environment for sensitive cell lines and supports high-quality results across molecular biology applications.

For researchers seeking a dependable Lab Reagent that ensures consistent growth, reduced stress, and reproducible outcomes, DMEM Low Glucose Pyruvate stands out as a trusted solution. Whether used in primary cell culture, metabolic research, or downstream applications involving Blot Reagents, this reagent empowers laboratories to perform with confidence and precision.